Some of the topics and discussions that were presented in the last conference of 2008, have been selected to form, in part, the contents of this book. However, the main aim of the book, in particular the concern of both editors, is the collating of the latest research results and interpretations of ultrasound-induced bio-effects, interactions and related safety issues. Therefore the book is structured in two parts: clinical issues and technical-practical issues to bio-effects and medical device safety topics.